Name: Ragada El-Damanawi

Theme: Diabetes CPC

OPTION LIST

A	Indogenous insulin	I	Metabolic Alkalosis
B	Exogenous insulin	J	Irritable bowel syndrome
C	Autonomic neuropathy	K	Cortisol
D	Respiratory Alkalosis	L	Coronary heart disease
E	Glucagon	M	Ectopic ACTH-producing tumour
F	Adrenal adenoma	N
G	Cushing's disease	O
H	Diabetic ketoacidosis	P

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. A 34 year old obese woman presents to her GP complaining of polyuria and polydipsia. Her blood pressure is 145/95mmHg and her whole blood glucose level is 12.0mmol/L. Further examination reveals she has a moon face and purple striae. Which hormone is most likely to be in excess.

2. A diabetic patient presents unconscious. Arterial blood gases reveal the following; pH 7.9 and paCO₂ 8.4. What is the metabolic abnormality.

3. A diabetic patient presents to A&E with muscle weakness, cramps and hypotonia. She was only recently placed on insulin replacement therapy. Investigations reveal hypokalaemia. Assuming the patient is otherwise healthy, which hormone is most likely to be responsible for the potassium levels.

4. A 48 year old man presents with pigmented skin, hyperglycaemia and a cushingoid appearance. A high dose dexamethasone test revealed there was a significant suppression of cortisol by day 2 of the test. What is the most likely cause of this glucocorticoid excess.

5. A 52 year old woman with a 20 year history of type II diabetes mellitus is referred to the gastroenterology clinic because she has recently developed episodic diarrhoea. What is the most likely complication of diabetes in this patient.

ANSWERS

1. K

2. I

3. B

4. G

5. C